We'll create fresh WordPress site with Crop-Thumbnails installed. You have 20 minutes to test the plugin after that site we'll be deleted.
The plugin provides the functionality to adjust the crop region of cropped images. It add buttons to the edit-pages and media-dialog to access a crop-editor.
In the crop-editor you can choose one or more (if they have the same ratio) imagesizes and cut-off the part of the image you want.
The plugin is especially useful for theme developers who want to keep full control over cropped image sizes. If you want to dive even deeper, you can get informations about the hooks and filters on the github page of the plugin.